Effect of Levamisole on the Biological ...
URL: http://www.ijnese.org/paperInfo.aspx?ID=4838
Deoxyuridine (UDR) is a potent antiviral drug could be labeled with radioiodine. 125IUDR was prepared by electrophilic substitution using iodogen as an oxidizing agent which produce yield above 90%, at pH 7 with heating on a water bath to 75 oC within 10-15 minute as a reaction time. The labeled drug was found to be stable for 48 h. Biodistribution study of 125I-UDR in ascites bearing mice reflects great uptake of radioactivity in tumor sites. 125I-UDR uptake in ascites was increased by combined use of leva
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| id | 1efd1a39-014a-42ef-ad80-924894b6470d |
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| state | active |